(E)-4-[bis(trideuteriomethyl)amino]-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]but-2-enamide
Pelitinib-d6
CAS: 1325223-34-4
Molecular Formula: C24H17ClD6FN5O2
(E)-4-[bis(trideuteriomethyl)amino]-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]but-2-enamide - Names and Identifiers
| Name | Pelitinib-d6 |
| Synonyms | Pelitinib-d6 [2H6]-Pelitinib (E)-4-[bis(trideuteriomethyl)amino]-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]but-2-enamide |
| CAS | 1325223-34-4 |
(E)-4-[bis(trideuteriomethyl)amino]-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]but-2-enamide - Physico-chemical Properties
| Molecular Formula | C24H17ClD6FN5O2 |
| Molar Mass | 473.960093868 |
| Storage Condition | -20°C |
(E)-4-[bis(trideuteriomethyl)amino]-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]but-2-enamide - Introduction
Pelitinib-d6 (Pelitinib-d6), a labeled compound used in chemical studies, is a deuterated derivative of Pelitinib. The following is a description of the nature, use, manufacture and safety information of the Pelitinib-d6:
Nature:
-chemical formula: C24H18D6Cl2N4O3
-Molecular weight: 465.4g/mol
-Appearance: White solid
-Melting Point: 176-178 ° C
-Solubility: Soluble in some organic solvents
Use:
Pelitinib-d6 is mainly used as an internal standard compound in pharmacokinetic studies and drug metabolism enzyme studies. It can be used to determine drug elimination, drug metabolism and drug concentration in vivo. By using Pelitinib-d6 as an internal standard, the concentration of Pelitinib in the sample can be accurately measured, thereby understanding the information of drug metabolism and pharmacodynamics.
Preparation Method:
A common method for preparing Pelitinib-d6 is to use the synthetic route to replace the hydrogen atom in Pelitinib with a deuterium atom. Specific preparation methods may require synthetic chemistry expertise and laboratory equipment.
Safety Information:
Because Pelitinib-d6 are primarily used for research purposes, limited toxicity and safety data are available. When using this compound, it is necessary to follow appropriate laboratory practices and safe practices, such as wearing personal protective equipment, working in a well-ventilated area, etc. If you need to use the Pelitinib-d6, please refer to the safety data sheet (SDS) and operating instructions provided by the supplier to ensure safe use and handling.
Nature:
-chemical formula: C24H18D6Cl2N4O3
-Molecular weight: 465.4g/mol
-Appearance: White solid
-Melting Point: 176-178 ° C
-Solubility: Soluble in some organic solvents
Use:
Pelitinib-d6 is mainly used as an internal standard compound in pharmacokinetic studies and drug metabolism enzyme studies. It can be used to determine drug elimination, drug metabolism and drug concentration in vivo. By using Pelitinib-d6 as an internal standard, the concentration of Pelitinib in the sample can be accurately measured, thereby understanding the information of drug metabolism and pharmacodynamics.
Preparation Method:
A common method for preparing Pelitinib-d6 is to use the synthetic route to replace the hydrogen atom in Pelitinib with a deuterium atom. Specific preparation methods may require synthetic chemistry expertise and laboratory equipment.
Safety Information:
Because Pelitinib-d6 are primarily used for research purposes, limited toxicity and safety data are available. When using this compound, it is necessary to follow appropriate laboratory practices and safe practices, such as wearing personal protective equipment, working in a well-ventilated area, etc. If you need to use the Pelitinib-d6, please refer to the safety data sheet (SDS) and operating instructions provided by the supplier to ensure safe use and handling.
Last Update：2024-04-09 21:04:16
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CAS: 1325223-34-4
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CAS: 1325223-34-4
Tel: 18301782025
Email: 3008007409@qq.com
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QQ: 3008007409
Product Name: Pelitinib-d6 Visit Supplier Webpage Request for quotation
CAS: 1325223-34-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1325223-34-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
(E)-4-[bis(trideuteriomethyl)amino]-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]but-2-enamide
(5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YLMETHYL)-HYDRAZINE
2-amino-1-{3-nitrophenyl}-5-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6,7,8-hexahydro-3-quinolinecarbonitrile
1350989-37-5
N'-[[3-(3,4-dimethoxyphenyl)sulfonyl-1,3-oxazolidin-2-yl]methyl]-N-(3-morpholin-4-ylpropyl)oxamide
iso-Carthamin
Dicyandiamide formaldehyde ammonium polymer
1451392-41-8
N-(PYRIDIN-4-YL)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLA
98534-57-7
(5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YLMETHYL)-HYDRAZINE
2-amino-1-{3-nitrophenyl}-5-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6,7,8-hexahydro-3-quinolinecarbonitrile
1350989-37-5
N'-[[3-(3,4-dimethoxyphenyl)sulfonyl-1,3-oxazolidin-2-yl]methyl]-N-(3-morpholin-4-ylpropyl)oxamide
iso-Carthamin
Dicyandiamide formaldehyde ammonium polymer
1451392-41-8
N-(PYRIDIN-4-YL)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLA
98534-57-7